The story of (-)/- Epicatechin began as a feel good story that ended in heartbreak. All over the world, bodybuilders who were expecting mythical muscle gains were instead heartbroken. A flavanol found in the cocoa plant and green tea, Epicatechin, generated keen interest from the supplement industry. Research in rodents suggested Epicatechin demonstrated an ability to suppress a protein in the body, myostatin, which prevents the increase of muscle size and differentiation. Since Olympus Labs is always on the leading edge of new ingredient research, we took a risk on Epicatechin and released EP1C. Regrettably, the majority of customers did not experience a noticeable increase in strength because it was discovered the bioavailability of the Epicatechin in humans is poor.
Undeterred by the setback, Olympus Labs devoted extensive time and expense to develop a delivery system to resolve the bioavailability issue. That effort produced PhytoFUSETM, an enhanced delivery system that research had shown could enhance the potency of Epicatechin anywhere from 200 to 600%. The next chapter of epicatechin commenced with EP1C UNLEASHED which users responded much better to and it subsequently grew in popularity. At the end of a story, however, there is an epilogue, which may further explain and in some cases provide a preview of a sequel.
In this case, there is an EP1LOGUE; simply put, it is the end of mediocrity. A new story has begun where the reputation of Epicatechin will be reconstructed. Olympus Labs does not accept defeat because DemiGods can persevere through any challenge. Our R&D team sought to complement Epicatechin PhytoFUSETM with innovative and effective compounds to finally establish some credibility for the ingredient. The outcome is nothing short of remarkable as EP1LOGUE is a powerful muscle builder, an intense pump inducer, and exercise enhancer. EP1LOGUE represents the moment where mere mortals transcend into DemiGods.
The anchor ingredient in EP1LOGUE is Epicatechin PhytoFUSETM.at a substantial dose of 600mg, a never before seen dose in ANY Epicatechin product. What separates EP1LOGUE from other Epicatechin products on the market, however, is the complementary ingredients that give the Epicatechin PhytoFUSETM a turbo boost. That boost is accomplished with the addition of an ingredient we brought to the market in RE1GN, VASO-6™, at 300mg. VASO-6™ is an innovative ingredient which we dubbed “Super Epicatechin”. It was first studied and funded through the University of South Florida and it significantly increases vasodilation (it stimulates nitric oxide levels at levels 10 times greater than Citrulline), stimulates blood flow, and activates muscle hypertrophy.
The formula is then perfected with a new and innovative compound that, once again, Olympus Labs introduces to the supplement industry called Urolithin B. Urolithin B is an innovative ingredient with research showing that it can inhibit protein catabolism while simultaneously increase protein synthesis. Urolithin B is essentially a bodybuilder’s dream; a natural ingredient that helps to build lean muscle while preventing muscle breakdown. Urolithin B is more active at the androgen receptor than testosterone, and more effective than insulin when it comes to upregulating muscle protein synthesis. We included Urolithin B in EP1LOGUE at a significant dose of 150mg to serve as the perfect complement to epicatechin and VASO-6™.
It is time to make it RE1GN with an innovative and multi-faceted supplement that goes beyond muscle building to enhance blood flow, endurance and body composition. It starts with the trifecta of Epicatechin PhytoFUSETM, VASO-6™, and Urolithin B; a new chapter begins where men become K1NGS, it begins with EP1LOGUE.
Directions: As a dietary supplement take 2 capsules 30-45 minutes prior to working out. On off days, take 1 capsule in the morning and 1 capsule in the afternoon.
- Barnett C et al. Food Funct., 2015,6, 824-833. DOI: 10.1039/C4FO00596A. Pharmacokinetic, partial pharmacodynamic and initial safety analysis of (−)-epicatechin in healthy volunteers.
- Jimenez et al. Free Radic Biol Med. 2012 Jan 1;52(1):70-9. doi:10.1016/ j.freeradbiomed.2011.09.015. Epub 2011 Sep 22. Epicatechin lowers blood pressure, restores endothelial function, and decreases oxidative stress and endothelin-1 and NADPH oxidase activity in DOCA-salt hypertension.
- Ciaraldi, T et al. J Nutr Biochem. Effects of (−)-epicatechin on molecular modulators of skeletal muscle growth and differentiation
- Dept of Pharmacology. Fitzpatrick D et al. Isolation and Characterization of Endothelium-Dependent Vasorelaxing Compounds from Grape Seeds. 2000.
- Dept of Pharmacology. Fitzpatrick D et al. Vasodilating Procyanidins Derived from Grape Seeds. 2002.
- Lee S-J et al. PLoS ONE 12(4): e0175271. https://doi.org/10.1371/journal. Pone.0175271. 2017. Epicatechin elicits MyoD- dependent myoblast differentiation and myogenic conversion of fibroblasts.
- Rodriguez, J et al. 2017 – Journal of Cachexia, Sarcopenia and Muscle – Wiley. Urolithin B, a newly identified regulator of skeletal muscle mass
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