THE NATURAL RECOMP STACK
WHAT IS THE NATURAL RECOMP STACK?
+1 BOTTLE OF IGNIT3
+1 BOTTLE OF EP1C UNLEASHED
+1 BOTTLE OF STR3NGTH UNLEASHED
HOW DO I TAKE THE NATURAL RECOMP STACK?
IGNIT3- ASSESS TOLERANCE BY TAKING 2-3 CAPSULES IN THE AM AND THEN AN ADDITIONAL 2 CAPSULES LATER IN THE EARLY AFTERNOON.
EP1C UNLEASHED- TAKE 2 CAPSULES PRE-WORKOUT AND 1 CAPSULES ON OFF DAYS WITH MEALS.
STR3NGTH UNLEASHED- TAKE 2 CAPSULES PRE-WORKOUT AND 2 CAPSULES ON OFF DAYS WITH MEALS.
As the human race has evolved over time there have been several positive advancements in technology, commerce, and medicine that have been beneficial for society. However, there has been negative impacts that have accompanied those advancements. Our lives have become saturated with various tasks leaving little time leftover for exercise, proper nutrition and rest. Furthermore, the typical western diet consisting of an excessive amount of high fat and high-sugar, overly processed foods has led to excessive weight gain in some individuals.
At the same time, there is tremendous pressure in our society to be fit and lean. There is no shortage of companies catering to this demographic. The supplement market is so oversaturated with fat burners that many are overwhelmed by all the options. Unfortunately, all of these products over promise and deliver mediocre results. Even fat burner supplements from reputable companies are only mildly effective. As a result, the consumer has devolved into a state of cynicism and has drifted further away from their target weight. So what can be done to TR1UMPH over this barrier? Your friends at Olympus Labs are here to help you.
The DemiGods at Olympus Labs have conjured up a fat burning formula so advanced and aggressive your guilt will turn into pride as you evolve past genetic barriers to reveal a fitter version of yourself. Olympus Labs presents IGNIT3; an explosive fat incinerator! IGNIT3 is like nothing you have seen before, it is truly a revolutionary product. So what differentiates IGNIT3 from all the other fat burners out there? It is quite simple actually, Olympus Labs underwent an extensive research process to develop the ultimate fat burning blend, backed by clinical science. Several ingredients were considered and rejected because they did not satisfy our strict criteria of Innovation, Value and Results.
A supplement formula does not necessarily need to contain a new ingredient to be innovative. Although IGNIT3 includes relatively new and emerging ingredients like Eria Jarensis and J. Regia, the innovation lies within the combination of mechanisms of action IGNIT3 targets. The two aforementioned ingredients, Eria Jarensis and J. Regia are combined with Rauwolfia Serpentina in the Adrenergic Enhancing Trifecta blend that act upon the sympathetic nervous system aid in fat loss. We are excited as you are about that blend alone, but IGNIT3 targets four more pathways for a total of 5 synergistic pathways. The AMPlified Fat Incinerating Matrix with St. John’s Wort Extract, Gynostemma Pentaphyllum Leaf Extract and Caffeine targets the activated protein kinase (AMPK) to regulate metabolic function.
The Brown Fat + Thyroid Modulating & Total PPAR Domination blend covers the remaining three pathways. The blend consists of Aframomum Melegueta which activates Brown Adipose Tissue (BAT) which leads to thermogenesis, Ginger Root Extract for BAT activation and to regulate the thyroid hormone and Olive Leaf Extract which also activates BAT. Olive Leaf Extract and the final two ingredients, Sesamol and Haematococcus Pluvialis Extract all activate peroxisome proliferator-activated receptors (PPARs) to stimulate your metabolism and adipogenesis, the inhibition of fat storage in the body.
Take a quick glance at the product label of IGNIT3 and it is clear that this is not your average fat burner. Although you may recognize some of the ingredients from some other fat burning supplements, we challenge you to look closer at those formulas. Is it just 1-2 effective ingredients accompanied with poor performing and cheap fillers? Are the doses comparable? IGNIT3 utilizes 11, yes 11, beneficial ingredients at effective doses backed by clinical studies. But that’s not all, as always, Olympus Labs uses superior extracts for superior results.
That is exactly where other fat burner supplements fail, they contain random ingredients that simply do not complement each other. The manufacturers of said products clearly have no regard for the time and hardwork you put into looking your best. Their sole motivation is to profit from your misfortune. Olympus Labs would never compromise our morals and resort to such a practice. IGNIT3 targets 5 different pathways to ensure you obtain noticeable results. Olympus Labs is here to help you get back on track towards your weight loss goals. We have generated the spark to IGNIT3 your thermogenic furnace!
Adrenergic Enhancing Trifecta:
The advances in the field of medicine over the years has made new and exciting supplements available. We utilize three such ingredients in the Adrenergic Enhancing Trifecta blend; Rauwolfia Serpentina, Eria Jarensis and J. Regia. Adrenergic substances act upon the sympathetic nervous system which activates a sequence of nerve cell firing and chemical release of epinephrine (adrenaline), norepinephrine in the blood stream. The release of these chemicals can be utilized to aid in fat loss. Although there is limited clinical data on these ingredients, the anecdotal feedback is quite compelling, which formed the basis for their inclusion in IGNIT3.
Rauwolscine, also known as α-yohimbine, is an alkaloid of Rauwolfia Serpentina. It is an alpha-2 adrenergic antagonist, that causes increases in epinephrine and norepinephrine in the blood stream. When exposed to epinephrine and norepinephrine, alpha-2 receptor sites inhibit lipolysis, the breakdown of fat. Since rauwolscine acts as an alpha-2 blocker it reverses that action and stimulates lipolysis.
There are a few studies that confirm that rauwolscine binds with comparable nanomolar affinity to alpha 2 adrenoceptors and the nonadrenergic 5-HT autoreceptors sites in human frontal cortex membranes. The studies all concluded that rauwolscine has agonistic properties at the level of 5-HT autoreceptors
Eria Jarensis is an orchidaceae alkaloid, meaning it is derived from the orchid family of flowering plants. It is the only known plant derivative to contain N-phenethyl dimethylamine. Phenethylyamines (PEA) Increases levels of epinephrine and norepinephrine that can stimulate beta-adrenergic receptors located on adipose (fat) tissue to release fatty acids into circulation as a fuel source. However, PEAs effects are relatively short-lived because the compound is broken down by the MAO-B enzyme within hours. N-Phenethyl dimethylamine rectifies that issue so you can realize the thermogenic benefits without having to dose the ingredient every few hours for it to be effective as you would PEA. Therefore, Eria Jarensis has become popular as a supplement for its energy and thermogenic benefits.
- Regia is a source of various psychoactive alkaloids and Olympus Labs uses a custom extract of it in IGNIT3. It is no longer a secret, J. Regia is truly an amazing and potent ingredient. But what may not be quite as well known is how multidimensional J. Regia is. It was included in the best pre-workout on the market, CONQU3R UNLEASHED and the pre-productivity supplement, ELIX1R for its focus and mood elevating benefits. However, It is also been observed to provide extreme energy and can suppress appetite, therefore J. Regia can be useful when dieting.
AMPlified Fat Incinerating Matrix:
The AMPlified Fat Incinerating Matrix will IGNIT3 your thermogenic furnace with 900mg of St. John’s Wort Extract, 450mg of Gynostemma Pentaphyllum Leaf Extract and 300mg Caffeine. This matrix was specifically designed to stimulate AMP-activated protein kinase (AMPK). AMPK is an enzyme that regulates metabolic function. During periods of energy stress, AMPK promotes glucose transport and glycolysis for ATP production, while it is thought to inhibit anabolic glycogen synthesis by suppressing the activity of glycogen synthase (GS) to maintain the energy balance in muscle. Paradoxically, chronic activation of AMPK causes an increase in glycogen accumulation in skeletal and cardiac muscles. That amazing energy you feel from IGNIT3? That would be the fat being incinerated!
St. John’s wort extract is herb that grows natively in areas of Asia and has been used for centuries for health purposes. The leaves and flowers of this herb contain hypericin and pseudohypericin. It is has been shown that both compounds specifically inhibit protein kinase C and shows antiproliferative activity against mammalian cells. St. John’s wort extract helps improve energy and alertness. It can also relieve stress and anxiety. However we included St. John’s wort extract in IGNIT3 because it has been identified as an inhibitor of adipogenesis.
Adipogenesis is a multistep process of cell differentiation where pre-adipocytes become mature adipocytes, or insulin-sensitive cells. An increase in the number and size of adipocytes causes white adipose tissue (WAT) to expand and this can lead to obesity, hence the reason inhibition of adipogenesis is beneficial.
St. John’s Wort is a significant CYP3A4 inducer, an enzyme involved in the metabolism of several pharmaceuticals drugs. If you are using any other pharmaceuticals, consult a medical professional before supplementation of St. John’s Wort to ensure those other drugs do not interact with CYP3A4.
In animal studies St. John’s Wort (SJW) extracts inhibited insulin-sensitive glucose uptake in mature fat cells. In follow-up studies, the effects of SJW have been further investigated on insulin action in both murine and human fat cells. It was shown that SJW also reduced insulin-sensitive glucose uptake in human adipocytes. Moreover, two constituents of SJW, hypericin (HI) and hyperforin (HF) were shown to modulate adipocyte development and insulin action in mature adipocytes. These studies concluded that SJW has significant effects on adipogenesis and insulin-stimulated glucose uptake.
In a double blind, randomized, placebo-controlled study, 23 subjects overweight healthy adults were separated into 1 of 3 groups. Group A consumed 975 mg of C aurantium extract, 528 mg of caffeine, and 900 mg of St. John’s Wort daily for 6 weeks; group B received a maltodextrin placebo; and group C received nothing and served as the control group. During the trial the participants were given guidance by a registered dietitian to follow an 1800-kcal/d American Heart Association Step One diet and performed a 3-day/week circuit training exercise program under the supervision of an exercise physiologist. During the exercise sessions, subjects achieved approximately 70% of age-predicted maximum heart rate. Compared with subjects in the placebo and control groups, subjects in the treatment group lost a significant amount of body weight (1.4kg). They also lost a significant amount of body fat (an average change of 2.9%). In terms of actual fat loss, group A lost a significant amount (3.1kg), whereas the control group demonstrated a tendency toward fat loss. The researchers concluded that the combination of C aurantium extract, caffeine, and St. John’s Wort is safe and effective when combined with mild caloric restriction and exercise for promoting both body weight and fat loss in healthy overweight adults.
Gynostemma Pentaphyllum leaf extract, sometimes referred to as Southern Ginseng, is a herb that has been typically been used in Asian countries as a treatment for type 2 diabetes and inflammation. Do not confuse Gynostemma Pentaphyllum with Panax Ginseng as they are two very different herbs. Gynostemma Pentaphyllum stimulates fat oxidation and glucose uptake by activating AMP-activated protein kinase (AMPK).
Caffeine increases focus, mental alertness and reduces symptoms of fatigue due to its ability to produce higher dopamine levels in areas of the brain that are linked to “attention”. It also increases energy expenditure and lipolysis which made it an easy choice to include in IGNIT3.
A double-blind study in healthy subjects who had a moderate habitual caffeine consumption investigated the effect on placebo and 100, 200, and 400 mg oral caffeine on energy expenditure, plasma concentrations of substrates and hormones, blood pressure, and heart rate. Caffeine dose dependently increased energy expenditure and the thermogenic response was positively correlated with the response in plasma caffeine (r = 0.52; p less than 0.018), plasma lactate (r = 0.79; p less than 0.000001), and plasma triglyceride (r = 0.53; p less than 0.02). These results indicate an increase in energy expenditure and thermogenic response from caffeine consumption.
A study was conducted to determine the relationship between paraxanthine (caffeine’s major dimethylxanthine metabolite) and free fatty acid (FFA) mobilization after intravenous caffeine administration. 10 men received a dose of 4mg of caffeine per kilogram of lean body mass. Venous blood samples were obtained before dosing and at multiple time intervals (5, 10, 15, 30, 45, 60, 90, 120, 150, and 180 minutes). Serum levels of FFA, glycerol, caffeine, and paraxanthine were determined in duplicate. Concentrations of FFA and glycerol were corrected for plasma volume changes. A high negative correlation was seen between decreases in caffeine and increases in FFA (r = -0.90) and a high positive correlation was seen between the appearance of paraxanthine and FFA (r = 0.93). It was concluded that paraxanthine may play a role in increased lipolysis after caffeine administration in humans.
Brown Fat + Thyroid Modulating & Total PPAR Domination:
As promised, IGNIT3 targets every major fat burning pathway. IGNIT3 includes 240mg of Aframomum Melegueta, 40mg of Ginger Root Extract and 400mg of Olive Leaf Extract for their ability to activate Brown Adipose Tissue (BAT). BAT is responsible for thermogenesis under normal conditions or during a dieting phase. It regulates whole-body energy expenditure and body fat content. Even though it activates BAT, our prime motivation in including Olive Leaf Extract is its ability to act upon the thyroid which can increase energy expenditure and ameliorate obesity, diabetes and metabolic disorders. Furthermore, Olive Leaf Extract has been shown to act upon the PPARγ receptor.
Peroxisome proliferator-activated receptors (PPARs) are ligand-activated transcription factors of the nuclear hormone receptor superfamily. There are three subtypes: PPARα, PPARγ, and PPARβ/δ. Activation of PPAR-α reduces triglyceride levels and is involved in regulation of energy homeostasis. Activation of PPAR-γ causes insulin sensitization and enhances glucose metabolism, whereas activation of PPAR-β/δ enhances fatty acids metabolism. IGNIT3 includes 200mg of Sesamol for its activation of PPAR-α and PPAR-γ and 240mg of the PPAR-α activator, Haematococcus Pluvialis Extract.
6-paradol is an extract of Grains of paradise (Aframomum Melegueta) a species of the ginger family, Zingiberaceae. It is an aromatic ketone which gives it a pungent, peppery taste. 6-paradol is known to activate thermogenesis in BAT and thus is a beneficial ingredient for the regulation of weight loss and weight maintenance. Furthermore, it has been shown that 6-paradol is a more potent paradol analogue compared to others with longer acyl chain lengths which is exactly what you want to IGNIT3 the metabolic furnace.
A single-blind, randomised, placebo-controlled, crossover designed study was conducted with 19 healthy males to examine the effects of the Grains of paradise (GP, Aframomum melegueta) extract on whole-body energy expenditure (EE) and to analyse its relation to BAT activity in men. Results from a test method that assesses BAT activity showed considerable uptake into the adipose tissue of the supraclavicular and paraspinal regions (BAT positive) in twelve subjects. The remaining seven showed no detectable uptake (BAT negative). Within 4 weeks after the examination, whole-body EE was measured at 27°C before and after oral ingestion of GP extract (40 mg). The resting EE of the BAT-positive group did not differ from that of the BAT-negative group. After GP extract ingestion, the EE of the BAT-positive group increased within 2 h to a significantly greater (P<0·01) level than that of the BAT-negative group. Placebo ingestion produced no significant change in EE. These findings suggest that oral ingestion of GP extract increases whole-body EE through the activation of BAT in human subjects.
Ginger contains pungent phenolic substances collectively known as gingerols. 6-Gingerol is the major pharmacologically-active component of ginger. 6-gingerol is known to have anti-cancer, anti-inflammatory and anti-oxidative properties. Ginger and its constituents have also been reported to possess gastro-protective and cholesterol-lowering properties. However, it is included in IGNIT3 because it can stimulate the peroxisome proliferator-activated receptor δ (PPARδ). As a PPARδ agonist, 6-gingerol will causes weight loss through increased energy expenditure and the browning of white fat.
A study was conducted to examine the antiobesity effect of dietary ginger extract (GE) in vivo with mice and the mechanism of action in vitro with human skeletal muscle myotubes. In the in vitro component of the study, 6-shogaol and 6-gingerol acted as specific PPARδ ligands and stimulated PPARδ-dependent gene expression in cultured human skeletal muscle myotubes. An analysis of cellular respiration revealed that pretreating cultured skeletal muscle myotubes with GE increased palmitate-induced oxygen consumption rate, which suggested an increase in cellular fatty acid catabolism. The mice treated with GE showed increased energy expenditure and diet-induced obesity was attenuated. GE also increased the number of Type I muscle fibers, improved running endurance capacity and upregulated PPARδ-targeted gene expression in skeletal muscle and the liver. These results demonstrated that sustained activation of the PPARδ pathway with GE attenuated diet-induced obesity and improved exercise endurance capacity by increasing skeletal muscle fat catabolism. These results showed that 6-Shogaol and 6-gingerol may be responsible for the regulatory effects of dietary ginger on PPARδ signaling.
A 30 day study was conducted where high-fat diet (HFD) induced obese rats were treated orally with a daily dose of gingerol (25, 50 and 75 mg kg-1). A lorcaserin, a pharmaceutical weight loss drug, treated group (10 mg kg-1) was included for comparison. The levels of body weight, glucose, lipid profile and insulin, insulin resistance, leptin, amylase and lipase were increased significantly (P < 0.05) in HFD rats. Rats treated with gingerol and fed a HFD showed significantly (P < 0.05) decreased glucose levels, body weight, leptin, insulin, amylase, lipase plasma and tissue lipids when compared to normal control. The effect at a dose of 75 mg kg-1 of gingerol was more pronounced than that of the dose 25 mg kg-1 and 50 mg kg-1 . The lorcaserin-treated group also manifested similar effects to those of gingerol. These results indicate that supplementation with 6-gingerol may suppress obesity induced by a high fat diet and it might be a promising adjuvant therapy for the treatment of obesity and its complications.
Oleuropein is the major phenolic compound found in the leaves and oil from olives. It possesses antioxidant, anti-inflammatory and anti-atherogenic effects and suppresses proliferation of fat cells in the body. Oleuropein has also been found to exert anti-adipogenic effects through direct inhibition of PPARγ. Furthermore, it has been shown to enhance thermogenesis by increasing the uncoupling protein 1 (UCP1) in Inducible Brown Adipose Tissue (IBAT) and urinary noradrenaline and adrenaline secretions.
The antiobesity effect of oleuropein was investigated in mice that were fed with a normal diet, HFD-40% fat of total energy) and HFD-supplemented with 0.03% oleuropein for 10 weeks. Oleuropein significantly reduced HFD-induced body weight gain and visceral adiposity. Oleuropein also significantly reversed the HFD-induced elevations of adipogenic related gene expression involved in WNT10b- and galanin-mediated signalings in adipose tissue of mice. Consistent with the in vivo findings, oleuropein dose-dependently suppressed lipid accumulation in 3T3-L1 cells during preadipocyte differentiation. Additionally, exposure of the 3T3-L1 preadipocytes to oleuropein resulted in a marked attenuation of the secreted frizzled-related protein 2 (WNT inhibitor) or galanin (galanin receptor agonist) induced cellular lipid accumulation. These results suggest that oleuropein has a protective effect against HFD-induced adiposity in mice and can reduce body weight gain and visceral adiposity.
A study with 3T3-L1 (mouse) cells treated with oleuropein between 10 and 400 μM concentrations did not affect activity of PPARα or PPARβ/δ. In fact, PPARγ activity, either basal or rosiglitazone activated, was inhibited by oleuropein. These findings indicate that oleuropein may exert anti-adipogenic effects through direct inhibition of PPARγ transcriptional activity.
A study was conducted to measure the degree of thermogenesis in interscapular brown adipose tissue (IBAT), and noradrenaline and adrenaline secretions in rats when supplemented with a phenolic compound, oleuropein, in extra virgin olive oil (EV-olive oil). In Experiment 1, rats were given a high-fat diet (control diet) with the oleuropein supplementation of 1, 2 or 4 mg/kg of diet (0.1, 0.2 or 0.4% oleuropein diet, respectively). After 28 d of feeding, body weight, perirenal adipose tissue, epididymal fat pad, and plasma triglyceride, free fatty acid and total cholesterol concentrations were reduced by the 0.1, 0.2 or 0.4% oleuropein diet and were significantly lowest in rats fed the 0.4% oleuropein diet, as compared with those of rats fed with the control diet. The content of uncoupling protein 1 (UCP1) in IBAT and urinary noradrenaline and adrenaline excretions were significantly higher in rats fed the 0.1 or 0.2% oleuropein diet, as compared with those of rats fed with the control diet, although there were no significant differences in rats fed the 0.4% oleuropein diet. In Experiment 2, the effects of oleuropein on noradrenaline and adrenaline secretion were evaluated. The intravenous administration of oleuropein and oleuropein aglycone significantly increased plasma noradrenaline and adrenaline concentrations. Furthermore, oleuropein aglycone induced the secretions of noradrenaline and adrenaline about ten fold more potently than oleuropein. These results indicate that oleuropein enhances thermogenesis by increasing the UCP1 content in IBAT and noradrenaline and adrenaline secretions in rats.
Sesamol is a phenol derivative of sesame oil. It is generated from sesamolin by roasting sesame seeds or through a bleaching process of sesame oil. It is a natural potent antioxidant and anti-inflammatory ingredient that has been found to have antimutagenic properties and is an efficient scavenger of the entire range of reactive oxygen species (ROS), validated by several tests. This is an important characteristic due to the fact that increased oxidative stress and inflammation is the direct cause of the development and proliferation of cardiometabolic syndrome (CMetS) in obese individuals. In addition, sesamol has been found to be a PPAR-γ modulator.
An animal study was conducted to determine the potential role of sesamol in chronic high-cholesterol/high-fat diet (HFD)-induced cardiometabolic syndrome (CMetS). Rats were fed with HFD (55% calorie from fat and 2% cholesterol) for 60 days to induce obesity, dyslipidemia, insulin resistance (IR), hepatic steatosis and hypertension. On the 30th day, rats with total cholesterol >150 mg/dl were considered hypercholesterolemic and administered sesamol 2, 4 and 8 mg/kg per day for the next 30 days. Sesamol treatment decreased IR, hyperinsulinemia, hyperglycemia, dyslipidemia, TNF-α, IL-6, leptin, resistin, highly sensitive C-reactive protein (hs-CRP), hepatic transaminases and alkaline phosphatase, along with normalization of adiponectin, nitric oxide and arterial pressures in a dose-dependent fashion. Increased TBARS, nitrotyrosine and decreased antioxidant enzyme activities were also amended in HFD rats. Similarly, sesamol normalized hepatic steatosis and ultrastructural pathological alteration in hepatocytes, although the effect was more pronounced at 8 mg/kg. Furthermore, hepatic PPARγ, PPARα and e-NOS protein expressions were increased, whereas LXRα, SERBP-1c, P-JNK and NF-κB expression were decreased by sesamol treatment. Based on these findings sesamol may be an effective treatment for CMetS.
Haematococcus Pluvialis is a freshwater species of chlorophyta, a division of green algae. It contains the antioxidant Astaxanthin which can lower adiponectin levels, a protein that is involved in regulating glucose levels and the breakdown of fatty acid levels.
In an SHR/NDmcr-cp (cp/cp) rat model oral administration of dietary astaxanthin oil (ASX-O) of 50 mg/kg/day for 22 weeks induced a significant reduction in arterial blood pressure in SHRcp. It also significantly reduced the fasting blood glucose level, homeostasis index of insulin resistance (HOMA-IR), and improved insulin sensitivity. The results also showed an improved adiponectin level, a significant increase in high-density lipoprotein cholesterol, a significant decrease in plasma levels of triglycerides, and nonesterified fatty acids. Additionally, ASX showed significant effects on the white adipose tissue by decreasing the size of the fat cells. These findings suggest that ASX improves insulin resistance through an increase of glucose uptake and by regulating the level of circulating lipid metabolites and adiponectin.
61 non-obese subjects with fasting serum triglyceride of 120-200mg/dl and without diabetes or hypertension participated in a placebo-controlled study to validate previous astaxanthin studies in animals. The subjects were randomly selected to receive astaxanthin in doses of 0, 6, 12, 18 mg/day for 12 weeks. Body mass index (BMI) and LDL-cholesterol were unaffected at all doses, however, triglyceride decreased, while HDL-cholesterol increased significantly. Multiple comparison tests showed that 12 and 18 mg/day doses significantly reduced triglyceride, and 6 and 12 mg doses significantly increased HDL-cholesterol. Serum adiponectin was increased by astaxanthin (12 and 18 mg/day), and changes of adiponectin correlated positively with HDL-cholesterol changes independent of age and BMI. These results suggest that astaxanthin consumption improves triglyceride and HDL-cholesterol in conjunction with increased adiponectin in humans.
You are likely familiar with the impressive line of supplements that Olympus Labs produces to help you CONQU3R your workouts. Now we provide a dynamic formula with IGNIT3 to CONQU3R fat.
With the 3 potent matrices in IGNIT3, we specifically target 5 fat burning pathways so you don’t miss any opportunities to incinerate the fat. There are adrenergic antagonists to stimulate lipolysis, AMPK activators to regulate metabolic function and BAT activators to stimulate thermogenesis. IGNIT3 also targets the thyroid hormone to increase energy expenditure and burn fat and includes several ingredients that activate PPARs which will stimulate your metabolism and inhibit adipogenesis.
Check the label on the others fat burners available. It is highly doubtful they contain anywhere close to the 11 effective ingredients in IGNIT3. In addition, as you have come to expect, Olympus Labs uses superior extract than the competition. Furthermore, every ingredient in IGNIT3 is adequately dosed to deliver results. So if you want look your best, you need to supplement with the best.
Put the past behind you and forge a new destiny. Join the ranks of a DemiGod or DemiGoddess and IGNIT3 your thermogenic furnace.
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The vast majority of supplement companies continue to release underdosed and unproven products. They attempt to deceive the consumer with outlandish claims and snazzy marketing campaigns. When the consumer eventually catches on to these companies act, supplement companies then revert to other duplicitous tactics, redesigning their container labels but they fail to make any meaningful changes to the actual product formula. Olympus Labs will not engage in such shady practices. We are committed to providing Innovation, Value and Results for the DemiGod Nation.
To hold true to that commitment the DemiGod R&D team is continuously striving to bring the most effective products to the supplement market. That process includes evaluating our own product lineup to determine whether any enhancements can be made based on new research, technologies, and or delivery systems. Case in point, was the impressive improvement we made to our (-)-epicatechin product, EP1C, with the release of EP1C UNLEASHED. Olympus Labs developed an exciting new delivery system, PhytoFUSETM, to increase the bioavailability and absorption of (-)-epicatechin. EP1C UNLEASHED established PhytoFUSETM as the premier methodology to increase the bioavailability and absorption of nutraceuticals ingredients, especially herbal ingredients and their extracts which tend to have poor absorption in the body.
The feedback from EP1C UNLEASHED has been exceptional, especially from non-responders to standard (-)-epicatechin. With the successful implementation of the PhytoFUSETM technology a wealth of possibilities was UNLEASHED. Join us DemiGod nation as Olympus Labs embarks on a revolution in supplementation with the PhytoFUSETM Series. The PhytoFUSETM Series will be a suite of supplements that embrace our commitment to Innovation and accomplishing the unimaginable!
Olympus Labs is proud to present the next wave of the PhytoFUSETM Series with STR3NGTH UNLEASHED and DERMASTR3NGTH UNLEASHED as another natural option to unearth your true anabolic potential. STR3NGTH UNLEASHED is the sequel to STR3NGTH, the capsule product featuring 5a-Hydroxy Laxogenin. While STR3NGTH represented a key development in the field of natural anabolics, at Olympus Labs we knew that the efficacy could be enhanced if only its bioavailability and absorption could be increased. To realize that objective, STR3NGTH UNLEASHED utilizes absorption enhancers with the now proven PhytoFUSETM technology to further enhance the bioavailability of Laxogenin. DERMASTR3NGTH UNLEASHED contains the same active ingredients, but in a transdermal version.
Not only does PhytoFUSETM technology help with absorption & bioavailability, but it also helps with distribution of the phytoFUSED ingredient in the body!
It will now be possible to realize the full potential of 5a-Hydroxy Laxogenin; increased strength, glucose uptake into the muscles and protein synthesis resulting in improved body composition. But that’s not all, it is believed Laxogenin can provide cortisol control, improve thyroid function and improve joint function. Do not be deterred from a prior experience with Laxogenin. There was doubt when EP1C UNLEASHED was released, but no longer! Olympus Labs converted the non-believers and the next wave in the PhytoFUSETM Series will correct the injustice that is found in the poor bioavailability and absorption of other laxogenin products.
STR3NGTH UNLEASHED and DERMASTR3NGTH UNLEASHED are here to UNLEASH the TRUE potential of this potent ingredient. It is totally understandable to get excited, Olympus Labs has accomplished another unthinkable feat and you, fellow DemiGod, are the benefactor. Get ready to obliterate the barriers to success and UNLEASH your TRUE STR3NGTH!
- Extreme Strength Gains
- Fuller Muscles
- Cortisol, Thyroid and Glucose Control
- Joint Repair
- Enhanced Absorption
5a-Hydroxy Laxogenin is a steroidal sapogenin isolated from Smilax sieboldi, a spirostanic analogue of the brassinosteroid. Brassinosteroids are plant-derived polyhydroxylated derivatives of 5a-cholestane, structurally similar to cholesterol-derived animal steroid hormones and insect ecdysteroids. They are found in small quantities in plants and foods such as pollen, seeds, and leaves. They are similar to animal steroids but function very differently at the cellular level. Plant brassinosteroids signal through a cell surface receptor kinase-mediated signal transduction pathway while animal steroid hormones act through the nuclear receptor family of transcription factors.
Brassinosteroids have a wide array of physiological and pharmacological effects in animals and insects including modulation of protein synthesis and carbohydrate metabolism. Research in animals suggest that brassinosteroids can stimulate protein synthesis and inhibit protein degradation in part by inducing Akt phosphorylation. Akt is a serine/threonine kinase that signals downstream of growth factor receptors and phosphoinositide-3 kinase PI3K. Akt stimulates glucose uptake, glycogen synthesis, and protein synthesis via Akt/mTOR and Akt/GSK-3β signaling networks and inhibits apoptosis and protein degradation in skeletal muscle by inactivating FoxO transcription factors leading to increased lean mass. In addition, unlike mammalian steroids, brassinosteroids are not hampered by androgenic side effects.
An animal study was conducted to assess the efficacy of the brassinosteroid, 28-Homobrassinolide (HB) on L6 rat skeletal muscle cells (EC50 4 μM). Oral administration of HB (20 or 60 mg/kg/d for 24 d) to healthy rats fed normal diet (protein content 23.9%) increased food intake, body weight gain, lean body mass, and gastrocnemius muscle mass as compared with vehicle-treated controls. The effect of HB administration increased slightly in animals fed a high-protein diet (protein content 39.4%). Both oral (up to 60 mg/kg) and subcutaneous (up to 4 mg/kg) administration of HB showed low androgenic activity and no direct binding to the androgen receptor in vitro. HB treatment was also associated with improved physical fitness of untrained healthy rats, as evident from a 6.7% increase in lower extremity strength, measured by grip test. In the gastrocnemius muscle of castrated animals, HB treatment significantly increased the number of type IIa and IIb fibers and the cross-sectional area of type I and type IIa fibers.
These findings suggest that oral application of HB triggers selective anabolic response with minimal or no androgenic side-effects and begin to elucidate the putative cellular targets for plant brassinosteroids in mammals. Furthermore, they indicate HB dose and time dependently stimulated protein synthesis and inhibited protein degradation in L6 rat skeletal muscle cells (EC50 4 μM), in part by inducing Akt phosphorylation (Fig.1 and Fig. 2)
Figure 1. Concentration and time-dependent effects of HB on protein synthesis and degradation in L6 rat myotubes.
Figure 2. HB increases Akt (Ser473) phosphorylation in L6 myotubes.
Unfortunately there is a lack of research and clinical trials on 5a-Hydroxy Laxogenin itself which is why several companies make product claims for Laxogenin based on its steroidal pharmaceutical anabolic counterpart. Although Olympus Labs never made products claims for our Laxogenin products, STR3NGTH and DERMASTR3NGTH based on this other pharmaceutical anabolic data, we did have high hopes based on the data cited above. Since 5a-Hydroxy Laxogenin has been available for a sufficient time period we were able to validate its efficacy as a bodybuilding supplement. Through anecdotal feedback we learned that actual results from STR3NGTH were similar to EP1C, where some users experienced modest strength increases while others experienced little to no results. Fortunately, the transdermal version, DERMASTR3NGTH yielded much better results but still did not coincide with the potential benefits based on the research on Brassinosteroids. We will seek to remedy that as we did with (-)-epicatechin by pairing Laxogenin with the proven PhytoFUSETM technology.
PhytoFUSETM – Enhanced Delivery System
STR3NGTH UNLEASHED and DERMASTR3NGTH UNLEASHED utilize a unique delivery technology, PhytoFUSETM, to enhance the bioavailability and absorption of 5a-Hydroxy Laxogenin. On top of this they help with distribution of the phytoFUSED ingredient in the body! Olympus Labs does not spend copious amounts of money on marketing campaigns, instead we spend available funds on research like the substantial investment in the PhytoFUSETM delivery system. The results DemiGods have seen from EP1C UNLEASHED leave no doubt that PhytoFUSETM is an effective enhanced delivery system. What other company can claim that?
Research has shown that this method of delivery can enhance potency anywhere from 2x-6x! That means that STR3NGTH UNLEASHED and DERMASTR3NGTH UNLEASHED will be 200 – 600% more potent than any other Laxogenin product on the market! This enhanced delivery system, unique to Olympus Labs, utilizes specific lipids to complex with Laxogenin on a molecular level, allowing for greater solubility and enhanced bioavailability/absorption, helping to effectively shuttle the active ingredient to the intestines where it can be taken up while preventing degradation throughout the process. This means that more ingredient is delivered to the site where it can be utilized effectively, ready to be delivered to the bloodstream and flood your muscles with potent myogenic factors needed to transcend into becoming a demigod!
With the success of EP1C UNLEASHED, it was a no brainer to apply the PhytoFUSETM technology to other ingredients that are inhibited by poor bioavailability and absorption. Unbeknownst to us at the time we introduced EP1C UNLEASHED, we were embarking on the dawning of a new era of the PhytoFUSETM Series. STR3NGTH UNLEASHED and DERMASTR3NGTH UNLEASHED are here to unlock the TRUE potential of the potent ingredient, 5a-Hydroxy Laxogenin. Get ready to obliterate the barriers to success and UNLEASH your TRUE STR3NGTH!
Despite this exciting breakthrough, Olympus Labs will not relent, as you grow in the gym with STR3NGTH UNLEASHED and DERMASTR3NGTH UNLEASHED you can bet the PhytoFUSETM Series will grow. DemiGod nation, what will be the next TR1UMPH? Stay Tuned!
I TEST1FY that I will CONQU3R, I will ENDUR3, I will TR1UMPH, and UNLEASH the STR3NGTH needed to crush any barrier put forth before me!
Directions: As a dietary supplement take 2 capsules daily with meals.
- Iglesias-Arteaga M et al. J. Braz. Chem. Soc. vol.16 no.3a São Paulo May/June 2005. A convenient procedure for the synthesis of 3b-hydroxy-6-oxo-5a-steroids. Application to the synthesis of laxogenin.
- Kubo S e al. Phytochemistry. 1992 Jul;31(7):2445-50. Steroidal saponins from the rhizomes of Smilax sieboldii.
- Debora E et al. FASEB J. 2011 Oct; 25(10): 3708–3719. doi: 10.1096/fj.11-181271. Anabolic effect of plant brassinosteroid
- Kidd P et al. Altern Med Rev. 2005 Sep;10(3):193-203. A review of the bioavailability and clinical efficacy of milk thistle phytosome: a silybin-phosphatidylcholine complex (Siliphos).
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Once again, Olympus Labs has set the bar for the category of natural anabolics with its reformulation of EP1C – EP1C Unleashed!
We have not strayed from the core value of our highly praised product, EP1C, but have only improved upon it. EP1C Unleashed still provides the high quality (-)/- epicatechin backed by our 3rd party purity tested lab analysis that you should demand from your supplements. We have also added additional ingredients and the latest in delivery absorption technology to improve bioavailability of the product. This ensures that you get the most out of your experience and produces even better results!
EP1C Unleashed provides:
- Increased strength and power output
- Increased endurance / stamina
- Enhanced vascularity
- Fat oxidation
- Muscle growth and differentiation
- Overall health benefits
The key ingredient to EP1C Unleashed is the inclusion of (-)/- epicatechin, a flavanol found in cocoa seeds and green tea. While the health benefits of (-)/-epicatechin (Epi) have been known for centuries, recent research has demonstrated that this flavanol may be useful for treating the age-related decline in muscle mass and associated strength, or sarcopenia, due to its action as a myostatin inhibitor. You may be familiar with myostatin, as it is a protein involved in preventing the increase of muscle size and differentiation, so blocking its action would be beneficial to those seeking additional muscle mass. Initial studies demonstrated that administration of Epi for 5 days increased follistatin (which binds to and inhibits myostatin) by 2.5 times. And in a pilot study with human subjects treated for 1 week with Epi, changes to markers of muscle differentiation were demonstrated, in addition to increases in hand-grip strength. Specifically, the study with epi demonstrated that the ratio of follistatin/myostatin was increased by almost 50%!
But there are also several other benefits to Epi, including reduced cardiovascular risk, enhanced exercise capacity and enhanced oxidative capacity, as well as increased angiogenesis (ie, creation of blood vessel formation) and improved vascular functioning via a NOS-dependent mechanism. Importantly, recent findings with satellite cells – precursors of new muscle growth and differentiation – identified that nitric oxide is a key messenger for maintaining function and enhancing proliferation of these precursor cells. All of these properties make Epi a very promising myostatin inhibiting compound.
Another well-known polyphenol is epigallocatechin gallate (EGCG), a constituent in tea that has been studied in a host of conditions, from weight loss to cancer to osteoarthritis and Alzheimer’s. In addition, EGCG has been investigated for potential influence on parameters of endurance and lipid oxidation. However, both Epi and EGCG suffer from the known problem of bioavailability, with absorption of oral Epi occurring at less than 50%. Many plant derived compounds are hampered by their poor oral bioavailability – meaning that the amount of active ingredient that your body is able to use after ingestion, may be very little, and in some cases too little to actually have the desired effect.
However, while the anti-oxidant properties of EGCG are beneficial, the inclusion in EP1C Unleashed was a two-fold strategic choice, as coadministration of other polyphenols with Epi has been shown to enhance its bioavailability. Specifically, research on gallate catechins, such as EGCG, has been shown to increase the intestinal absorption of Epi. But simply adding EGCG with Epi would not elicit enough of a change for the results we really want. So, we did not stop there, we had to provide something that no other company has done…
PhytoFUSETM – Enhanced Delivery System
EP1C Unleashed also utilizes a unique delivery technology, PhytoFUSETM, to further enhance the bioavailability of Epi. While the poor bioavailability of catechins has hampered use, PhytoFUSETM helps to overcome these issues. That’s right, we poured funding into the research & development and testing of a completely new delivery system. What other company can claim that? Research has shown that this method of delivery can enhance potency anywhere from 2x-6x! That means that EP1C Unleashed is 200 – 600% more potent than Epi alone! This enhanced delivery system, unique to Olympus Labs, utilizes specific lipids to complex with Epi on a molecular level, allowing for greater solubility and enhancing bioavailability, helping to effectively shuttle and prevent degradation en route to the intestines where it can be taken up. This means that more ingredient is delivered to the site where it can be utilized effectively, ready to be delivered to the bloodstream to flood your muscles with potent myogenic factors.
Real World Results
Once again, we could have just released this supplement at this point, confident on the research in the literature. But Olympus Labs drives results based on real world testing. We invested in independent alpha testing, to ensure that the changes made to our formula would pay off. And while we knew that the results of EP1C Unleashed were going to be positive, the results exceeded even our own expectations. In tester results, users reported breaking PR after PR, nearly unlimited endurance in between reps and sets, breezing through cardio, and enhanced vascularity. And this was from only a few days in. Additionally, significant body composition effects were very apparent on a bulk, a cut, and especially during a recomp phase. But don’t just take our word for it. Here are real results from some of our testers:
“Still noticing the same effects I have since the beginning. Increased sweat, endurance has been crazy, good pump and vascularity, muscle hardening. Seriously feeling like I barely need to rest at all when I sit the weight down. Muscles have been feeling fuller when reaching super compensation with my carb refeeds as well.” – carmineb1
“I started my 2 caps pwo and lol this stuff has now gone to borderline mild prohormone status for me. 10/10 pumps, great focus and just amazing strength.” – [email protected]
“Muscle Hardness/pump- 10/10 This is one of the very best attributes of this product in my opinion. I did not take a pwo and trained fasted for the majority of the run. The pumps I received were some of the very best I’ve ever had. Muscles would feel harder and full even into the next day… I started this log at 170lbs and ended at 177lbs for a solid 7lb gain!!!! This is an awesome gain to me for a natural product with very little body fat gain! Endurance was tenfold increased running this product. Workouts lasted longer with more reps and exercises. Felt like the energizer bunny all through the cycle!” – [email protected]
“The positives are still the same-DOMs, vascularity, endurance, fat loss/maintain strength and mass. If I had to make a direct comparison it would be very similar to [11-kt]” – Afi140
“For me [EP1C Unleashed] outshines mild ph’s (or not so mild) in the endurance department. Rest time in between sets is ridiculously short…never had that experience with any hormonal compound. For pumps it goes on par with mild ph’s… zero lethargy…which does happen to me on a lot of ph’s, aas.” – edje007
“So standouts this week have been two things, noticeable body composition and recovery. I trained 6 days this week and could have easily done the whole 7 no problems… Other mentioned things, volume and weights continuing to progress. Body composition wise, as I mentioned earlier in the week my waist size has significantly reduced… That is impressive, a natural supplement actually allowing me to increase my work load and causing fat loss and muscle gain simultaneously.” – NoAddedHmones
“This product most notable effect is tied between endurance and recovery. Both Are out of this world. Never had a supp provide the magnitude or even ball park it. I was able to consistently progressively over load in volume, weight( power days) and frequency over the entire course of the run. Effects kicked in within a few days and only got better. Other effects which are worth noting are the pumps. This was the only supp bar caffeine i used pwo and i was consistently achieving outrageous pumps. The GDA effect also is worth mentioning, talk about vein city after a large carb meal.” – NoAddedHmones
EP1C Unleashed is truly unlike any product that has come before it. While other companies may use deceptive marketing tactics to confuse the consumer, Olympus Labs will continue to innovate and provide the highest quality products, backed by independent third party verification, clinical science and real world results, to ensure that you can attain the physique that mere mortals only dream about.
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Disclaimer: While we work to ensure that product information is correct, on occasion manufacturers may alter their ingredient lists. Actual product packaging and materials may contain more and/or different information than that shown on our Web site. We recommend that you do not solely rely on the information presented and that you always read labels, warnings, and directions before using or consuming a product. For additional information about a product, please contact the manufacturer. Content on this site is for reference purposes and is not intended to substitute for advice given by a physician, pharmacist, or other licensed health-care professional. You should not use this information as self-diagnosis or for treating a health problem or disease. Contact your health-care provider immediately if you suspect that you have a medical problem. Information and statements regarding dietary supplements have not been evaluated by the Food and Drug Administration and are not intended to diagnose, treat, cure, or prevent any disease or health condition. Olympus Labs assumes no liability for inaccuracies or misstatements about products.